William married Hannah Hastings on 22 Oct 1764 in Shrewsbury or Templeton, Worcester, Massachusetts, USA. Hannah (daughter of Joseph Hastings, Jr. and Hannah Hastings) was born about 14 Aug 1745 in Massachusetts, USA; died on 25 Oct 1832 in Shrewsbury, Worcester, Massachusetts, USA. [Group Sheet] [Family Chart]

1. Asa Knowlton, Sr. was born on 31 Aug 1765 in Templeton, Worcester, Massachusetts, USA; died in 1825 in Shrewsbury, Worcester, Massachusetts, USA.
2. Hannah Knowlton was born on 14 Jun 1767 in Templeton, Worcester, Massachusetts, USA; died on 8 Mar 1793 in Shrewsbury, Worcester, Massachusetts, USA.
3. Artemas Knowlton was born on 6 Sep 1772 in Templeton, Worcester, Massachusetts, USA; died on 16 May 1834 in Shrewsbury, Worcester, Massachusetts, USA.
4. Susanna Knowlton was born on 15 Jan 1775 in Templeton, Worcester, Massachusetts, USA; died on 23 Aug 1847.
5. William Knowlton was born on 20 Jun 1777 in Shrewsbury, Worcester, Massachusetts, USA.
6. Seth Knowlton, Dr. was born on 11 May 1781 in Shrewsbury, Worcester, Massachusetts, USA; died on 12 Apr 1832 in Shrewsbury, Worcester, Massachusetts, USA.
7. Joseph Hastings Knowlton was born on 22 Mar 1785 in Shrewsbury, Worcester, Massachusetts, USA; died on 25 Aug 1848.