Francis married Mary Bond on 13 Feb 1837 in likely Clarksville, , New York, USA . Mary (daughter of Captain Charles Bond, Sr. and Susanna Stearns) was born on 12 Sep 1807 in likely Watertown, Middlesex, Massachusetts, USA; died on 20 Aug 1842 in Clarkesville, , New York, USA. [Group Sheet] [Family Chart]

1. Susan Dewey Prescott was born in 25 Jan or Jun 1838 in Middlefield,,New York, USA; died on 18 Dec 1863.
2. Charles Francis Prescott was born on 20 Jun 1842 in Litchfield,Herkimer,New York, USA; died in Sep 1842.