Isaac married Jerusha Garfield on 1 Jan 1767 in Watertown, Middlesex, Massachusetts, USA. Jerusha (daughter of Joseph Garfield and Abigail Fuller) was born in Watertown, Middlesex, Massachusetts, USA; was christened on 28 Feb 1742 in Waltham, Middlesex, Massachusetts, USA. [Group Sheet] [Family Chart]

1. Anna Walker was born on 8 Nov 1767 in Weston, Middlesex, Massachusetts, USA.
2. Isaac Walker was born on 8 Dec 1768 in Weston, Middlesex, Massachusetts, USA; died on 15 May 1835 in Tyringham,Berkshire,Massachusetts, USA; was buried in Old Center Cemetery,Monterey,Berkshire,Massachusetts, USA.
3. Jonathan Walker was born on 16 Dec 1769 in Weston, Middlesex, Massachusetts, USA; died on 16 Apr 1772 in Weston, Middlesex, Massachusetts, USA.
4. Jerusha Walker was born on 12 Jul 1772 in Weston, Middlesex, Massachusetts, USA; died on 12 Jun 1832 in Sandisfield, Berkshire, Massachusetts, USA; was buried in Sandisfield Center Cemetery, Cemetery, Sandisfield, Berkshire, Massachusetts, USA.
5. Jacob Walker was born on 20 Jun 1774 in Weston, Middlesex, Massachusetts, USA.
6. Samuel Walker was born in 1781.