Isaac married Abigail Hyde on 17 Feb 1732 in Newton, Middlesex, Massachusetts, USA. Abigail (daughter of Jonathan Hyde, Sr. and Hannah Dana) was born about 9 Jan 1712 in Newton, Middlesex, Massachusetts, USA. [Group Sheet] [Family Chart]

1. Isaac Stowell, Jr. was born about 1733 in Middlesex, Massachusetts, USA; died on 3 Mar 1820 in Dedham, Norfolk, Massachusetts, USA.
2. Jacob Stowell, Sr. was born on 3 Apr 1736 in Dedham, Norfolk, Massachusetts, USA; died on 13 Nov 1806 in Windsor, Windsor, Vermont, USA; was buried in Old South Church Cemetery, Windsor, Windsor, Vermont, USA.
3. Abigail Stowell was born on 6 Oct 1737 in Dedham, Norfolk, Massachusetts, USA; died on 6 Apr 1774.
4. Joseph Stowell was born on 1 May 1739 in Dedham, Norfolk, Massachusetts, USA; died on 31 Dec 1780.
5. Mary Stowell was born in Dec 1741 in Dedham, Norfolk, Massachusetts, USA; died on 25 Aug 1755 in Dedham, Norfolk, Massachusetts, USA.
6. Samuel Stowell was born on 27 May 1743 in Dedham, Norfolk, Massachusetts, USA; died on 20 Jan 1826 in Gray, Cumberland, Maine, USA.
7. Captain Ebenezer Stowell was born on 22 Dec 1744 in Dedham, Norfolk, Massachusetts, USA; died on 9 Oct 1791 in Boston, Suffolk, Massachusetts, USA.
8. Lemuel Stowell was born on 25 Mar 1747 in Dedham, Norfolk, Massachusetts, USA ; died on 29 May 1832 in Dedham, Norfolk, Massachusetts, USA .
9. Thaddeus Stowell was born on 19 Apr 1750 in Dedham, Norfolk, Massachusetts, USA; died on 10 Jun 1750 in Dedham, Norfolk, Massachusetts, USA.
10. Thaddeus Stowell was born on 7 Aug 1751 in Dedham, Norfolk, Massachusetts, USA; died on 28 May 1786 in Washington, Sullivan, New Hampshire, USA.
11. Mary Stowell was born on 30 May 1755 in Dedham, Norfolk, Massachusetts, USA.