Isaac married Sarah Stratton on 1 Jun 1748 in Newton, Middlesex, Massachusetts, USA. Sarah (daughter of Ebenezer Stratton and Lydia Fuller) was born on 19 Nov 1725 in Cambridge, Middlesex, Massachusetts, USA; died in 1763 in Massachusetts, USA. [Group Sheet] [Family Chart]

1. Isaac Williams was born on 7 Sep 1748 in Massachusetts, USA.
2. Sarah Williams was born on 27 Aug 1750 in Newton, Middlesex, Massachusetts, USA; died on 1 Aug 1812 in Newton, Middlesex, Massachusetts, USA.
3. Abigail Williams was born on 10 Jul 1752 in Massachusetts, USA.
4. Ebenezer Williams was born on 28 Nov 1756 in Massachusetts, USA.
5. Ephraim Williams was born on 25 Feb 1760 in Massachusetts, USA.
6. Patty Williams was born on 2 Nov 1763 in Massachusetts, USA.