Samuel married Francis Elizabeth Griswold on 3 May 1864. Francis (daughter of George Griswold and Hannah Richards Jackson) was born on 3 Feb 1845 in Rockvale Township, , Ogle, Illinois, USA; died on 23 Oct 1916 in Oregon,Ogle,Illinois, USA; was buried in Riverview Cemetery,Oregon,Ogle,Illinois, USA. [Group Sheet] [Family Chart]

1. Ida E. McGruffin was born on 19 Dec 1864; died on 17 Apr 1940; was buried in Cedar Hill Cemetery,Mount Morris,Ogle,Illinois, USA.
2. Allie Maude McGruffin was born on 21 Sep 1866 in Illinois, USA; died in 1938; was buried in Riverview Cemetery,Oregon,Ogle,Illinois, USA.
3. Mary E. McGruffin was born on 29 Mar 1869 in Rockvale Township, , Ogle, Illinois, USA; died on 28 Jun 1947; was buried in Oakwood Cemetery,Mount Morris,Ogle,Illinois, USA.
4. Nellie E. McGruffin was born on 18 Aug 1870; died on 15 Nov 1870; was buried in Riverview Cemetery,Oregon,Ogle,Illinois, USA.
5. Margaret Hannah McGruffin was born on 15 Aug 1872; died on 4 Mar 1954.
6. Blanche Lenore McGruffin was born on 6 Jul 1875 in Rockvale Township, , Ogle, Illinois, USA; died on 19 Nov 1957 in San Diego, San Diego, California, USA; was buried in Rose Hill Cemetery,Manson,Calhoun,Iowa, USA.
7. Catherine B. McGruffin was born on 4 Aug 1877; died on 26 Oct 1895; was buried in Riverview Cemetery,Oregon,Ogle,Illinois, USA.
8. Talbot S. McGruffin was born on 15 Jun 1879; died on 29 Nov 1965.
9. Edith F. McGruffin was born on 27 Nov 1883; died on 21 Aug 1969.